Fetal distress and the levels of malondialdehyde (MDA): A meta-analysis

Purpose: To estimate the effect of malondialdehyde (MDA) level on fetal distress.
 Methods: Meta-analyses randomized controlled interventions were performed by searching 8 electronic databases (CNKI, VIP, CBM, WANFANG, Embase, PubMed, Cochrane, and Web Science) from 1980 – to date for trials determine any intrapartum distress. A metaanalysis within a frequentist framework was quality inconsistency assessed. Dual selection data abstraction conducted. The methodological meta-analyses assessed using AMSTAR, evidence GRADE. Random-effect models used pool results individual studies included in each meta-analysis.
 Results: total 1720 patients received MDA tests, showed that value experimental group 1.66 higher than control group. Heterogeneity between two groups high, suggesting choice blood source significantly affected result meta-analysis (p < 0.05). samples collected mothers highly heterogeneous, combined with 16 groups, effective amount reached (2.08) significant (z = 4.29, p This means increase maternal during maternal-fetal Secondly, cord heterogeneous collection group, random insignificant 0.94, > 0.05).
 Conclusion: Malondialdehyde reflects relationship distress adverse outcomes. Further research is needed confirm extent which they are related.